人类脑科学 | 科普讲座

最好的科普应该由科学家来做!将科学普及化也是对科学家专业能力的另一种体现。 2022全国科技活动周 中国图象图形学学会 科普云讲堂:人类生命周期的脑图表-带你通往心智健康之路 认知神经科学与学习国家重点实验室 探索大脑 你我同行:人脑暗能量与青春期

Read more

《自然》长文 | 人类生命周期脑图表

Bethlehem, R.A.I., Seidlitz, J., White, S.R., et al. Brain charts for the human lifespan. –Nature 604(7906): 525-533 (2022) “生长发育图表(growth chart)是公共卫生与健康领域的重要工具。它不仅可以揭示儿童发育(如身高体重)的一般规律,为生长发育(如营养摄入情况)评估提供健康参考,而且也可以为各类发育障碍发出预警信号,用于辅助诊断相关疾病,在家庭养育和临床实践中被广泛应用。” –《科学通报》-悦读科学-“彩巢计划”三部曲—测量(工欲效其事, 必先信其器)、队列(一生最好是少年)、理论(青春期的脑中乾坤) 摘要 在过去的几十年里,神经影像已经成为人类脑科学研究中普遍使用的工具。然而,与身高和体重等人体特征的生长发育图表相比[1],神经影像指标尚缺乏类似参考标准以量化个体差异。因此,我们建立了一个交互式的开放资源,通过已有的或将来采集的磁共振成像(Magnetic Resonance Imaging, MRI)数据样本评估大脑形态。为了将这些参考图表建立在现有的最大最广的数据集上,避免由全球人口多样性造成的MRI研究偏差,我们汇总了来自100多个研究中的101457名志愿者的123984次磁共振扫描影像,他们的年龄范围从孕115天到100岁(图1a)。基于大脑形态结构毕生发展的非线性轨迹[2]和变化率来量化大脑组织的体积和其他全局、局部指标的百分位数。绘制的脑图表发现了从未被揭示过的神经发育里程碑[3],在纵向发展评估中表现出很高的稳定性,并具备应对不同研究之间技术和方法差异的稳健性。同时,与非百分位数的MRI表型相比,脑图表百分位数显示出更高的遗传性,并为揭示神经和精神疾病的神经解剖变异模式提供了非典型大脑结构的标准化测量指标。总之,以多种常用神经影像表型常模轨迹作为基准,脑图表在量化个体变异的道路上迈出了重要一步。

Read more

Chinese Color Nest Project

Before we started this project, we were finishing a high-resolution (4mm) network map of the human brain connectome using functional imaging data from more than 1000 healthy adults across different stages of the postnatal lifespan (18-85 years) based upon the 1000 Functional Connectomes Project (Biswal et al., 2010; Zuo et al., 2012). This map was…

Read more

Developmental Neuroimaging Labs

Time, Space and Brain … The Brain is wider than the Sky. Emily Dickinson Every time we remember something from the past or imagine something that will happen in the future, we engage in mental time travel. Scientists discovered that, whether we mentally travel back into the past or forward into the future, some of…

Read more

BrainHack

NeuroView – Brainhack: Developing a culture of open, inclusive, community-driven neuroscience We have lots of cool projects coming … Go to the website for submitting your projects or joining in projects you are interested in!

Read more

Connectome Computation System 1.0

This page is under construction and you can visit CCS release at GitHub. Software DREAM Comes True Rhythms of the brain are generated by neural oscillations across multiple frequencies. These oscillations can be decomposed into distinct frequency intervals associated with specific physiological processes. In practice, the number and ranges of decodable frequency intervals are determined…

Read more

Crisis & Opportunity | Dev. Neurosci.

I posted the modified PDF version of the presentation by Professor F. Xavier Castellanos from New York University. He talked about this ‘Crisis and Opportunity’ story during the Brain Mind Development in Childhood and Adolescence Forum of the Inaugural Beijing Brain Conference (26 October 2020). Open science shares with the community, for reproducibility!

Read more

Brain Development | Growth Charts

Growth is a result of your child’s genetics, environment, and culture. When your children come to a well-child check, their pediatrician will measure their height and weight at each visit and head circumference when they are 3 years and younger. Not only can it be fun to see how much they have grown between visits,…

Read more

Developmental Population Neuroscience

Comparable to ‘Project Apollo’ and ‘Manhattan Project’ in last century, brain projects became a national-wide arena for scientific frontiers at the beginning of the 21st century. Of note, the most recent decade paralleled the remarkable development of the non-invasive and in-vivo human brain imaging technologies. Especially, the magnetic resonance imaging (MRI) have made significant progresses…

Read more